Description
The Agilent 1260 Infinity II Refractive Index Detector is a high-performance HPLC detector designed to excel in differential refractometry (DRI) applications, delivering outstanding results for both entry-level UHPLC and traditional HPLC experiments. It’s especially well suited for detecting compounds without chromophores, such as carbohydrates, lipids, and polymers, which can’t be detected using standard UV-based methods. The detector uses electronic temperature control (ETC) to maintain unmatched thermal and electronic stability, keeping a steady optical unit temperature of up to 55°C for consistent, reproducible results. Its thermal design allows for fast start-up, with initial setup typically completed in under two hours, and light intensity automatically adjusts to compensate for lamp degradation and flow cell staining over time. A built-in recycle valve allows users to maintain operating conditions without a full warm-up cycle, saving both time and solvent between runs.
Features:
- Electronic Temperature Control (ETC): Maintains steady optical unit temperature for consistent, reproducible measurements.
- Fast Start-Up: Initial setup typically completed in under two hours.
- Automatic Light Intensity Optimization: Compensates for lamp degradation and flow cell staining.
- Automatic Purge & Solvent Recycle Valves: Saves time and solvent by avoiding unnecessary warm-up cycles.
- GLP-Compliant Design: Early Maintenance Feedback (EMF) tracks instrument usage with user-selectable limits.
- Extensive Diagnostics: Leak detection, safe leak handling, and automated error detection/display.
- Broad Chemical Compatibility: Liquid contact materials include 316 stainless steel, PTFE, and quartz glass.
- Automated OQ/PV: Supports automated operational qualification/performance verification.
Specifications:
- Refractive index range: 1.00–1.75 RIU, calibrated
- Measurement range: ±600×10⁻⁶ RIU
- Short-term noise: <±1.25×10⁻⁹ RIU
- Drift: <200×10⁻⁹ RIU/hr
- Sample cell volume: 8 µL
- Max pressure: 5 bar (0.5 MPa)
- Max flow rate: 5 mL/min
- Optics temperature control: 5°C above ambient to 55°C
- Max data rate: Up to 74 Hz
- pH range: 2.3–9.5
- Line voltage: 100–240V~, ±10%
- Dimensions (H x W x D): 180 x 396 x 436 mm (7.1 x 15.6 x 17.2 in.)
- Weight: 15 kg (33 lbs)



